«СПОКОЙНЫЙ, СОЗНАТЕЛЬНЫЙ И СОТРУДНИЧАЮЩИЙ» ПАЦИЕНТ В РЕАНИМАЦИИ КАК СТРАТЕГИЯ ФАРМАКОЛОГИЧЕСКОЙ РЕГУЛЯЦИИ ЦИРКАДНОГО РИТМА (обзор литературы)
Аннотация
В статье освещены современные взгляды на роль мелатонина в регуляции циркадных циклов человека, а также указаны его основные метаболические эффекты – антиоксидантный, противовоспалительный, анальгезирующий, иммуномодулирующий, которые могут использоваться в лечении взрослых и детей с различной патологией.
Приведены сведения о возможной причинно-следственной связи десинхронизации секреции мелатонина и развития делирия и послеоперационных когнитивных расстройств у пациентов в критическом состоянии. Рассмотрена проблема глубокой седации больных в отделениях интенсивной терапии, предложены пути достижения уровня «минимально глубокой» эффективной седации больных с использованием парентерального и энтерального введения препаратов.
Литература
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2. Nseir S., Makris D., Mathieu D., Durocher A., Marquette C.H. Intensive care unit-acquired infection as a side effect of sedation. Crit Care. 2010; 14 (2): R30. doi: 10.1186/cc8907
3. Reade M.C., Finfer S. Sedation and delirium in the intensive care unit. N Engl J Med. 2014; 370: 444-454.
4. Kondili E., Alexopoulou C., Xirouchaki N., Georgopoulos D. Effects of propofol on sleep quality in mechanically ventilated critically ill patients: a physiological study. Intensive Care Med. 2012; 38: 1640-1646.
5. Pandharipande P., Ely E.W. Sedative and analgesic medications: risk factors for delirium and sleep disturbances in the critically ill. Crit Care Clin. 2006; 22 (2): 313-327.
6. Inouye S.K. Delirium in older persons. N Engl J Med 2006; 354: 1157-1165.
7. Ely E.W., Gautam S., Margolin R. [et al.] The impact of delirium in the intensive care unit on hospital length of stay. Intensive Care Med. 2001; 27 (12): 1892-1900.
8. Barr J., Fraser G.L., Puntillo K. [et al.] American College of Critical Care Medicine: Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Crit Care Med. 2013; 41: 263-306.
9. Shehabi Y., Riker R.R., Bokesch P.M. [et al.] SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group: Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients. Crit Care Med. 2010; 38: 2311-2318.
10. Pisani M.A., Kong S.Y., Kasl S.V. [et al.] Days of delirium are associated with 1-year mortality in an older intensive care unit population. Am J Respir Crit Care Med. 2009; 180: 1092-1097.
11. Milbrandt E.B., Deppen S., Harrison P.L. [et al.] Costs associated with delirium in mechanically ventilated patients. Crit Care Med. 2004; 32: 955-962.
12. Pandharipande P., Shintani A., Peterson J. [et al.] Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients. Anesthesiology. 2006; 104: 21-26.
13. Benedetti F., Pontiggia A., Bernasconi A., Colombo C., Florita M., Smeraldi E. Lormetazepam in depressive insomnia: new evidence of phase-response effects of benzodiazepines. Int Clin Psychopharmacol. 2004; 19: 311-317.
14. Dessap A.M., Roche-Campo F., Launay J.M. [et al.] Delirium and circadian rhythm of melatonin during weaning from mechanical ventilation: an ancillary study of a weaning trial. Chest. 2015; 148: 1231-1241.
15. Eckle T. Delirium-a dysfunctional circadian rhythm. Int J Anesth Res. 2016; 4: 1-3.
16. Olofsson K., Alling C., Lundberg D., Malmros C. Abolished circadian rhythm of melatonin secretion in sedated and artificially ventilated intensive care patients. Acta Anaesthesiol Scand. 2004; 48: 679-684.
17. Arendt J. Melatonin and the pineal gland: influence on mammalian seasonal and circadian physiology. Rev Reprod. 1998; 3: 13-22.
18. Walker C.K., Gales M.A. Melatonin receptor agonists for delirium prevention. Ann Pharmacother. 2017; 51: 72-78.
19. Tsuda A., Nishimura K., Naganawa E. [et al.] Ramelteon for the treatment of delirium in elderly patients: A consecutive case series study. Int J Psychiatry Med. 2014; 47: 97-104.
20. Sultan S.S. Assessment of role of perioperative melatonin in prevention and treatment of postoperative delirium after hip arthroplasty under spinal anesthesia in the elderly. Saudi J Anaesth. 2010; 4: 169-173.
21. Hatta K., Kishi Y., Wada K. [et al.] DELIRIA-J Group: Preventive effects of ramelteon on delirium: A randomized placebo-controlled trial. JAMA Psychiatry. 2014; 71: 397-403.
22. Al-Aama T., Brymer C., Gutmanis I. [et al.] Melatonin decreases delirium in elderly patients: A randomized, placebo-controlled trial. Int J Geriatr Psychiatry. 2011; 26: 687-694.
23. Baron R., Binder A., Biniek R., Braune S., Buerkle H., Dall P., Demirakca S., Eckardt R., Eggers V., Eichler I. [et al.] Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015) – short version. Ger Med Sci. 2015; 13: Doc19. doi: 10.3205/000223
24. Celis-Rodriguez E., Birchenall C., de la Cal M.A., Castorena Arellano G., Hernandez A., Ceraso D., Diaz Cortes J.C., Duenas Castell C., Jimenez E.J., Meza J.C. [et al.] Clinical practice guidelines for evidence-based management of sedoanalgesia in critically ill adult patients. Med Int. 2013; 37 (8): 519-593.
25. Shehabi Y., Bellomo R., Reade M.C., Bailey M., Bass F., Howe B., McArthur C., Seppelt I.M., Webb S., Weisbrodt L. Early intensive care sedation predicts long-term mortality in ventilated critically ill patients. Am J Respir Crit Care Med. 2012; 186 (8): 724-731.
26. Balzer F., Weiss B., Kumpf O., Treskatsch S., Spies C., Wernecke K.D., Krannich A., Kastrup M. Early deep sedation is associated with decreased in-hospital and two-year follow-up survival. Crit Care. 2015; 19: 197. DOI: 10.1186/s13054-015-0929-2
27. Shah F.A., Girard T.D., Yende S. Limiting sedation for patients with acute respiratory distress syndrome – time to wake up. Curr Opin Crit Care. 2017; 23 (1): 45-51.
28. Oddo M., Crippa I.A., Mehta S., Menon D., Payen J.F., Taccone F.S., Citerio G. Optimizing sedation in patients with acute brain injury. Crit Care. 2016; 20 (1): 128. doi:10.1186/s13054-016-1294-5
29. Martin J., Franck M., Fischer M., Spies C. Sedation and analgesia in German intensive care units: how is it done in reality? Results of a patient-based survey of analgesia and sedation. Intensive Care Med. 2006; 32 (8): 1137-1142.
30. Vincent J.L. Give your patient a fast hug (at least) once a day. Crit Care Med. 2005; 33 (6): 1225-1229.
31. Cigada M., Corbella D., Mistraletti G., Forster C.R., Tommasino C., Morabito A., Iapichino G. Conscious sedation in the critically ill ventilated patient. J Crit Care. 2008; 23 (3): 349-353.
32. Vincent J.L., Shehabi Y., Walsh T.S., Pandharipande P.P., Ball J.A., Spronk P., Longrois D., Strom T., Conti G., Funk G.C. [et al.] Comfort and patient-centred care without excessive sedation: the eCASH concept. Intensive Care Med. 2016; 42 (6): 962-971.
33. Walsh T.S., Kydonaki K., Antonelli J., Stephen J., Lee R.J., Everingham K., Hanley J., Phillips E.C., Uutela K., Peltola P. [et al.] Staff education, regular sedation and analgesia quality feedback, and a sedation monitoring technology for improving sedation and analgesia quality for critically ill, mechanically ventilated patients: a cluster randomised trial. Lancet Respir Med. 2016; 4 (10): 807-817.
34. Girard T.D., Kress J.P., Fuchs B.D., Thomason J.W., Schweickert W.D., Pun B.T., Taichman D.B., Dunn J.G., Pohlman A.S., Kinniry P.A. [et al.] Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial. Lancet. 2008; 371 (9607): 126-134.
35. Sessler C.N., Gosnell M.S., Grap M.J., Brophy G.M., O’Neal P.V., Keane K.A., Tesoro E.P., Elswick R.K. The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med. 2002; 166 (10): 1338-1344.
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Опубликована
2019-03-01
Как цитировать
КОЛЕСНИКОВ, А. Н. et al.
«СПОКОЙНЫЙ, СОЗНАТЕЛЬНЫЙ И СОТРУДНИЧАЮЩИЙ» ПАЦИЕНТ В РЕАНИМАЦИИ КАК СТРАТЕГИЯ ФАРМАКОЛОГИЧЕСКОЙ РЕГУЛЯЦИИ ЦИРКАДНОГО РИТМА (обзор литературы).
Университетская клиника, [S.l.], n. 1(30), p. 72-79, март 2019.
ISSN 1819-0464. Доступно на: <http://journal.dnmu.ru/index.php/UC/article/view/287>. Дата доступа: 17 ноя. 2024
doi: https://doi.org/10.26435/uc.v0i1(30).287.
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Обзоры
