PSYCHOEMOTIONAL STATUS AND CATECHOLAMINE METABOLISM IN PREGNANT WOMEN LIVING IN WARTIME CONDITIONS
Abstract
The aim of our study was to increase the effectiveness of a complex of therapeutic and preventive measures aimed at reducing the frequency of maternal and perinatal morbidity in pregnant women living in the region of military conflict by influencing the state of the psycho-emotional and sympathoadrenal system. The features of the psychoemotional status and urinary excretion of catecholamines in pregnant women living in the region of military conflict were studied. The effectiveness of therapeutic measures was studied in 46 pregnant women who received therapy according to a generally accepted method, who formed a comparison group. The main clinical group included 45 pregnant women who received a complex of therapeutic and preventive measures developed by us. The conducted studies indicate that pregnant women living in the region of military conflict, according to the Spielberger, Lusher test and the integral assessment of psychoemotional status, had an increased level of reactive anxiety, physical and mental endurance, self-regulation, reserves of compensatory mechanisms, violations of the level of functional capabilities of mental adaptation. Against this background, a decrease in the average excretion of adrenaline by 1.8 times and DOPA by 1.6 times and an increase in the level of dopamine in urine by 1.7 times compared with such indicators of healthy pregnant women was revealed. The high efficiency of differentiated physiotherapy, drug treatment and psychological support for pregnant women has been proven. The treatment of women in the main group allowed them to activate the sympathoadrenal system, increase its reserve capabilities, increase the excretion of catecholamines (adrenaline by 2.8 times; norepinephrine – 2.1; DOPA – 1.6; dopamine by 1.3 times) in urine compared with similar indicators in the comparison group (p<0.05). The effectiveness of the treatment was evidenced by a decrease in the frequency of obstetric pathology.
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